4-Hydroxy nebivolol hydrochloride

SKU:BHB21901430
Overview
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4-Hydroxy nebivolol hydrochloride (CAS 2717115-85-8) is a drug metabolite supplied as a solid. Relevant to GPCR/G Protein and Neuronal Signaling research. Molecular formula C22H26ClF2NO5, molecular weight 457.90 g/mol.
CAS Number 2717115-85-8
Molecular Weight 457.90 g/mol
Form Solid
Storage Powder -20°C; in solvent -80°C
Options selector
Catalog no. Size
HY-149503-500UG 500 μg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 500 μg
  • Lead time: shown per option in the variant selector.
  • Storage: Powder: -20°C, 3 years. In solvent: -80°C, 6 months; -20°C, 1 month.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: transfer to -20°C as soon as possible.
Field Specification
CAS no. 2717115-85-8
Applications
  • Functional Assay (In Vitro)
Molecular weight 457.90
Molecular formula C22H26ClF2NO5
SMILES FC1=CC=C2OC(C(CNCC(C3OC4=CC=C(C=C4C(C3)O)F)O)O)CCC2=C1.Cl
Form Solid
Storage Powder: -20°C, 3 years. In solvent: -80°C, 6 months; -20°C, 1 month.
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-149503
Main SKU BHB21901430
Drug Metabolites & Impurities

Compound Overview

4-Hydroxy nebivolol hydrochloride, also referred to as 4-OH nebivolol hydrochloride, is an active, hydroxylated β-blocking metabolite of nebivolol[1]. It is supplied as a white to off-white solid (C22H26ClF2NO5, MW 457.90).

Physical & Chemical Properties

CAS Number 2717115-85-8
Molecular Formula C22H26ClF2NO5
Molecular Weight 457.90 g/mol
Appearance Solid
Color White to off-white
SMILES FC1=CC=C2OC(C(CNCC(C3OC4=CC=C(C=C4C(C3)O)F)O)O)CCC2=C1.Cl
Signaling Pathway GPCR/G Protein; Neuronal Signaling; Metabolic Enzyme/Protease
Storage Powder: -20°C, 3 years. In solvent: -80°C, 6 months; -20°C, 1 month.
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Xiaoxia Hu, et al. Evaluation of 24 CYP2D6 Variants on the Metabolism of Nebivolol In Vitro. Drug Metab Dispos. 2016 Nov;44(11):1828-1831.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.

Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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