| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C24H33NO |
| Purity | |
| SMILES | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
5,6-Dihydroabiraterone is a metabolite of Abiraterone. Abiraterone itself is a potent, irreversible CYP17A1 inhibitor with antiandrogen activity and shows antitumor activity in CRPC (castration-resistant prostate cancer)[1][2]. It is supplied as a white to light yellow solid (C24H33NO, MW 351.52) at 96.51% purity.
Physical & Chemical Properties
| CAS Number | 219843-75-1 |
|---|---|
| Molecular Formula | C24H33NO |
| Molecular Weight | 351.52 g/mol |
| Purity | 96.51% |
| Appearance | Solid |
| Color | White to light yellow |
| SMILES | C[C@@]12C(C3=CC=CN=C3)=CC[C@@]1([H])[C@]4([H])CC[C@@]5([H])C[C@@H](O)CC[C@]5(C)[C@@]4([H])CC2 |
| Signaling Pathway | Metabolic Enzyme/Protease |
| Solubility | In Vitro: DMSO: 1 mg/mL (2.84 mM; Requires sonication and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) |
| Storage | 4°C, sealed storage, away from moisture and light. In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
In Vitro
| Solvent | Solubility | Notes |
|---|---|---|
| DMSO | 1 mg/mL (2.84 mM) | requires sonication and warming and heat to 60°C; use freshly opened DMSO (absorbed moisture lowers solubility) |
Aliquot the stock solution and store it at -80°C (up to 6 months) or -20°C (up to 1 month); sealed storage, away from moisture and light; avoid repeated freeze-thaw cycles.
Data provided by the manufacturer.
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