| Field | Specification |
|---|---|
| Alternative names | 3β-Hydroxy-5α-androstane |
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C19H32O |
| Purity | |
| SMILES | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
5α-Androstan-3β-ol, a saturated sterol also known as 3β-Hydroxy-5α-androstane, acts as an inverse agonist ligand of the constitutive androstane receptor (CAR). It increases AmB-channel conductance in a concentration-dependent manner[1][2]. It is supplied as a white to off-white solid (C19H32O, MW 276.46) at 99.99% purity.
Physical & Chemical Properties
| CAS Number | 1224-92-6 |
|---|---|
| Molecular Formula | C19H32O |
| Molecular Weight | 276.46 g/mol |
| Purity | 99.99% |
| Appearance | Solid |
| Color | White to off-white |
| SMILES | C[C@@]12[C@]3([H])[C@](CC[C@@]1([H])C[C@H](CC2)O)([H])[C@@]4([H])[C@](CC3)(CCC4)C |
| Signaling Pathway | Metabolic Enzyme/Protease |
| Solubility | In Vitro: DMSO: 14 mg/mL (50.64 mM; Requires sonication and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) |
| Storage | Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
In Vitro
| Solvent | Solubility | Notes |
|---|---|---|
| DMSO | 14 mg/mL (50.64 mM) | requires sonication and warming; use freshly opened DMSO (absorbed moisture lowers solubility) |
Aliquot the stock solution and store it at -80°C (up to 6 months) or -20°C (up to 1 month); avoid repeated freeze-thaw cycles.
Data provided by the manufacturer.
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