| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C10H13N5O4 |
| Purity | |
| SMILES | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
5'-Azido-5'-deoxythymidine is a nucleoside analogue that acts as a reverse transcriptase inhibitor. It mimics nucleosides and is incorporated into the viral DNA chain to terminate chain elongation, thereby inhibiting viral replication, and it is considered promising for research on retroviral infections such as AIDS[1][2]. It is supplied as a white to off-white solid (C10H13N5O4, MW 267.24) at 99.06% purity.
Physical & Chemical Properties
| CAS Number | 19316-85-9 |
|---|---|
| Molecular Formula | C10H13N5O4 |
| Molecular Weight | 267.24 g/mol |
| Purity | 99.06% |
| Appearance | Solid |
| Color | White to off-white |
| SMILES | O=C(C(C)=CN1[C@H]2C[C@H](O)[C@@H](CN=[N+]=[N-])O2)NC1=O |
| Signaling Pathway | Anti-infection |
| Solubility | In Vitro: DMSO: 8.33 mg/mL (31.17 mM; Requires sonication; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) |
| Storage | Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
[2]. Baraniak D. Synthesis of nucleoside-cinchona alkaloid conjugates via" click" chemistry[D]. Zakład Chemii Medycznej [nowa struktura organizacyjna], 2012.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
In Vitro
| Solvent | Solubility | Notes |
|---|---|---|
| DMSO | 8.33 mg/mL (31.17 mM) | requires sonication; use freshly opened DMSO (absorbed moisture lowers solubility) |
Aliquot the stock solution and store it at -80°C (up to 6 months) or -20°C (up to 1 month); avoid repeated freeze-thaw cycles.
Data provided by the manufacturer.
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