| Field | Specification |
|---|---|
| Target | |
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C21H26BrNO3 |
| Purity | |
| SMILES | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
5-HT2A receptor agonist-3 ((S,S)-9b) is an agonist of the 5-HT2A receptor, with a Ki of 2.5 nM for the human 5-HT2A receptor, and it shows 124-fold selectivity for 5-HT2A over the structurally similar 5-HT2C receptor[1]. It is supplied as an off-white to light yellow solid (C21H26BrNO3, MW 420.34) at 98.53% purity.
Physical & Chemical Properties
| CAS Number | 1391499-52-7 |
|---|---|
| Molecular Formula | C21H26BrNO3 |
| Molecular Weight | 420.34 g/mol |
| Purity | 98.53% |
| Appearance | Solid |
| Color | Off-white to light yellow |
| SMILES | COC1=C([C@H]2N[C@@H](CCC2)CC3=C(C=C(C(OC)=C3)Br)OC)C=CC=C1 |
| Target | Human 5-HT 2A Receptor, Human 5-HT 2C Receptor |
| Signaling Pathway | GPCR/G Protein; Neuronal Signaling |
| Storage | 4°C, protect from light. In solvent: -80°C, 6 months; -20°C, 1 month (protect from light). |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Biological Activity
Activity & Target
|
Human 5-HT2A Receptor 2.5 nM (Ki) |
Human 5-HT2C Receptor 310 nM (Ki) |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
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