| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | 6-Ethylchenodeoxycholic acid; 3α,7α-Dihydroxy-6α-ethyl-5β-cholan-24-oic acid; Obeticholic acid |
| Cas No. | |
| Form | White powder |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | May be dissolved in DMSO (50 mg/ml) and ethanol (30 mg/ml) |
| Source | Synthetic |
| Storage |
6-ECDCA, also known as Obeticholic Acid, is a potent and selective agonist of the farnesoid X receptor (FXR). It exhibits anti-inflammatory, anti-cholestatic, and autophagy-inducing properties.
While primarily studied in liver diseases such as primary biliary cholangitis, its ability to modulate metabolic and inflammatory pathways has sparked interest in neurodegenerative disease research. FXR signaling intersects with pathways involved in neuroinflammation, lipid metabolism, and mitochondrial function, making 6-ECDCA a candidate for exploring therapeutic strategies in disorders like Alzheimer’s and Huntington’s disease.
Classification: Not a hazardous substance or mixture.
Safety Phrases:
- S22 - Do not breathe dust.
- S24/25 - Avoid contact with skin and eyes.
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
6-ECDCA (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-590)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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