6BrCaQ-C10-TPP

SKU:BHB21901211
Overview
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6BrCaQ-C10-TPP (CAS 3036044-73-9) is an inhibitor. Relevant to Cell Cycle/DNA Damage and Metabolic Enzyme/Protease research. Molecular formula C45H47Br2N2O3P, molecular weight 854.65 g/mol.
CAS Number 3036044-73-9
Molecular Weight 854.65 g/mol
Storage See Certificate of Analysis
Options selector
Catalog no. Size
HY-144831-50MG 50 mg
HY-144831-100MG 100 mg
HY-144831-250MG 250 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 50 mg, 100 mg, 250 mg
  • Lead time: confirmed on inquiry for every option.
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: store as stated on the Certificate of Analysis; contact us if you need the condition before ordering.
Field Specification
CAS no. 3036044-73-9
Applications
  • Functional Assay (In Vitro)
Molecular weight 854.65
Molecular formula C45H47Br2N2O3P
SMILES CN1C(C(NC(C2=CC=C(C=C2)OCCCCCCCCCC[P+](C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)=O)=CC6=CC(Br)=CC=C61)=O.[Br-]
Storage Refer to Certificate of Analysis (CoA) for storage conditions
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-144831
Main SKU BHB21901211
Inhibitors

Compound Overview

6BrCaQ-C10-TPP is a potent inhibitor of the mitochondrial heat shock protein TRAP1, with antiproliferative activity across various human cancer cells (IC50 0.008-0.30 μM). It can also induce disturbance of the mitochondrial membrane[1]. It has a molecular formula of C45H47Br2N2O3P and a molecular weight of 854.65 g/mol.

Physical & Chemical Properties

CAS Number 3036044-73-9
Molecular Formula C45H47Br2N2O3P
Molecular Weight 854.65 g/mol
SMILES CN1C(C(NC(C2=CC=C(C=C2)OCCCCCCCCCC[P+](C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)=O)=CC6=CC(Br)=CC=C61)=O.[Br-]
Signaling Pathway Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Mathieu C, et al. Synthesis and antiproliferative activity of 6BrCaQ-TPP conjugates for targeting the mitochondrial heat shock protein TRAP1. Eur J Med Chem. 2022 Feb 5;229:114052.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.

Q.Why is there no price listed?
A.Every size of this product is quoted on inquiry. Send us the size you need and we will come back with price and lead time.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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