| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C42H40F3N7O7S5 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
A-1293102 is a potent, selective inhibitor of BCL-XL that kills BCL-XL-dependent tumor cells[1]. Its molecular formula is C42H40F3N7O7S5, with a molecular weight of 972.13 g/mol.
Physical & Chemical Properties
| CAS Number | 1565759-96-7 |
|---|---|
| Molecular Formula | C42H40F3N7O7S5 |
| Molecular Weight | 972.13 g/mol |
| SMILES | O=C(C1=C2C(CCN(C3=NC(C(NS(=O)(C4=CC(S(C(F)(F)F)(=O)=O)=C(C=C4)N[C@@H](CSC5=CC=CC=C5)CCN6CCOCC6)=O)=O)=CS3)C2)=CC=C1)NC7=NC8=CC=CC=C8S7 |
| Signaling Pathway | Apoptosis |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
[1]. Zhi-Fu Tao, et al.Structure-Based Design of A-1293102, a Potent and Selective BCL-XL Inhibitor. ACS Medicinal Chemistry Letters 2021 12 (6), 1011-1016.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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