| Field | Specification |
|---|---|
| Target | |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse ACE2 |
| Conjugate | |
| Purification | |
| Concentration | |
| Storage | |
| Storage buffer | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Scientific Background
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.
Product Overview
This polyclonal antibody, raised in Rabbit, recognizes ACE2. It is validated for Western Blot.
Validated Applications
| Applications | Western Blot |
|---|---|
| WB | 1:500-1:2000 |
Optimal dilutions should be determined by the end user for each application and sample type.
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse ACE2
Specifications
| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse ACE2 |
| Purification | Affinity Purification |
| Concentration | 330 μg/mL |
| Storage Buffer | PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH 7.4 |
| Calculated MW | 92kDa |
| Observed MW | 95kDa |
| UniProt # | Q9BYF1,Q8R0I0,Q5EGZ1 |
| Lead Time | 2-3 business days |
| Validity | 12 months |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | Ice packs |
| Target Synonyms | ACE 2;ACE related carboxypeptidase;ACE-related carboxypeptidase;ACE2;ACE2;ACEH;Angiotensin converting enzyme 2;Angiotensin converting enzyme homolog;Angiotensin converting enzyme like protein;Angiotensin I Converting Enzyme (peptidyl dipeptidase A) 2;Angiotensin I converting enzyme 2;Angiotensin-converting enzyme homolog;DKFZP434A014;EC 3.4.17;metalloprotease MPROT 15;Metalloprotease MPROT15;OTTHU |
Reactivity Notes
Validated reactivity: Human, Mouse, Rat. For other species, epitope conservation may allow cross-reactivity; confirm with appropriate controls.
Safety & Handling
This product is for research use only (RUO) and is not intended for diagnostic or therapeutic use. The formulation contains sodium azide; handle with standard laboratory precautions.
Related Products
Explore related antibodies and reagents for ACE2 research from Elabscience Biotechnology Co Ltd, or contact us for alternative formats.
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