| Field | Specification |
|---|---|
| Alternative names | N-(2-Acetamido)-2-aminoethanesulfonic acid |
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C4H10N2O4S |
| Purity | |
| SMILES | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
ACES, also known as N-(2-Acetamido)-2-aminoethanesulfonic acid, is a zwitterionic buffer with a working pH range of 6.8–7.2[1][2]. It is supplied as a white to off-white solid (C4H10N2O4S, MW 182.20) at 98.0% purity.
Physical & Chemical Properties
| CAS Number | 7365-82-4 |
|---|---|
| Molecular Formula | C4H10N2O4S |
| Molecular Weight | 182.20 g/mol |
| Purity | 98.0% |
| Appearance | Solid |
| Color | White to off-white |
| SMILES | O=C(N)CNCCS(=O)(O)=O |
| Solubility | In Vitro: H2O: 40 mg/mL (219.54 mM; Requires sonication) |
| Storage | Store at room temperature 3 years. In solvent: -80°C, 2 years; -20°C, 1 year. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
In Vitro
| Solvent | Solubility | Notes |
|---|---|---|
| H2O | 40 mg/mL (219.54 mM) | requires sonication |
Aliquot the stock solution and store it at -80°C (up to 2 years) or -20°C (up to 1 year); avoid repeated freeze-thaw cycles.
If water is used as the stock solvent, dilute to the working solution and sterilize it through a 0.22 μm filter before use.
In Vivo
Choose the formulation that suits the animal model and route of administration. Percentages are volume ratios of the final working solution. Prepare the working solution fresh on the day of dosing; if precipitation or phase separation occurs, gentle warming or sonication can help.
Direct preparation of the working solution
These formulations are prepared directly, without a DMSO stock; use them promptly after preparation.
Protocol 1
| Composition | PBS |
|---|---|
| Result | 16.67 mg/mL (91.49 mM); clear solution; requires sonication |
Data provided by the manufacturer.
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