| Field | Specification |
|---|---|
| Applications | |
| Molecular weight | |
| Molecular formula | C19H15NO3 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
AChE-IN-39 is an AChE inhibitor, with an IC50 of 0.058 μM, and it shows DPPH radical-scavenging activity. It improves cognitive impairment in an AlCl3-induced amnesia animal model and can be used in Alzheimer's disease research[1]. It has the molecular formula C19H15NO3 and a molecular weight of 305.33 g/mol.
Physical & Chemical Properties
| Molecular Formula | C19H15NO3 |
|---|---|
| Molecular Weight | 305.33 g/mol |
| SMILES | O=C(C1=CC2=C(C=CC=C2)O1)/C=C/NC3=CC(C(C)=O)=CC=C3 |
| Signaling Pathway | Neuronal Signaling |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Biological Activity
Activity & Target
0.058 μM (AChE)[1]
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
[1]. Somaia S. Abd El-Karim, et al. Discovery of novel benzofuran-based derivatives as acetylcholinesterase inhibitors for the treatment of Alzheimer's disease: Design, synthesis, biological evaluation, molecular docking and 3D-QSAR investigation. European Journal of Medicinal Chemistry. 2013, 115766.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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