| Field | Specification |
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| Target | |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Recombinant Mouse CD18 protein |
| Conjugate | |
| Purity | |
| Purification | |
| Concentration | |
| Storage | |
| Storage buffer | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Scientific Background
CD18 is a 95 kD protein, also known as integrin β2 subunit. It is expressed on all leukocytes. CD18, in association with integrin α chain CD11a, CD11b, and CD11c forms LFA-1, Mac-1, and αXβ2, respectively, and plays an important role in leukocytes adhesion. The CD18 integrin complexes bind ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, and fibrinogen. The M18/2 antibody is able to block tumor cell metastasis and enhance cell adhesion.
Product Overview
This monoclonal antibody (clone M18/2), raised in Rat, recognizes CD18. It is validated for Flow Cytometry, Neutralization.
Validated Applications
| Applications | Flow Cytometry, Neutralization |
|---|
Optimal dilutions should be determined by the end user for each application and sample type.
Immunogen
Recombinant Mouse CD18 protein
Specifications
| Host | Rat |
|---|---|
| Clonality | Monoclonal |
| Clone | M18/2 |
| Isotype | Rat IgG2a, κ |
| Conjugate | Unconjugated (AF/LE: azide-free, low endotoxin) |
| Species Reactivity | Mouse |
| Immunogen | Recombinant Mouse CD18 protein |
| Purification | Protein A/G Purified |
| Purity | >98% |
| Concentration | ≥ 1 mg/mL |
| Storage Buffer | Sterile PBS, pH 7.2 < 1.0 EU per mg of the antibody as determined by the LAL method. |
| UniProt # | P11835 |
| Gene ID | 16414 |
| Lead Time | 2-3 business days |
| Validity | 12 months |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Shipping | Ice packs |
| Target Synonyms | Integrin beta;ITGB;CD18;Cell surface adhesion glycoproteins LFA-1/CR3/p150+95 subunit beta;Complement receptor C3 subunit beta;Integrin beta-2;Itgb2;&beta-2 integrin-n |
Reactivity Notes
Validated reactivity: Mouse. For other species, epitope conservation may allow cross-reactivity; confirm with appropriate controls.
Safety & Handling
This product is for research use only (RUO) and is not intended for diagnostic or therapeutic use. The formulation contains sodium azide; handle with standard laboratory precautions.
Related Products
Explore related antibodies and reagents for CD18 research from Elabscience Biotechnology Co Ltd, or contact us for alternative formats.
Customization & Add-ons: Can't find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
