| Field | Specification |
|---|---|
| Alternative names | SIRT2 Inhibitor,Inactive Control |
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C23H13Cl2N3O2 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
AGK7 is a potent inhibitor of sirtuin 2 (SIRT2) that rescues alpha-synuclein toxicity and modifies inclusion morphology in a cellular model of Parkinson's disease. It also protects against dopaminergic cell death both in vitro and in a Drosophila model of Parkinson's disease[1]. It has the molecular formula C23H13Cl2N3O2 and a molecular weight of 434.27 g/mol.
Physical & Chemical Properties
| CAS Number | 304896-21-7 |
|---|---|
| Molecular Formula | C23H13Cl2N3O2 |
| Molecular Weight | 434.27 g/mol |
| SMILES | O=C(NC1=CC=CC2=C1N=CC=C2)/C(C#N)=C/C3=CC=C(O3)C4=CC(Cl)=CC=C4Cl |
| Signaling Pathway | Cell Cycle/DNA Damage; Epigenetics |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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