| Field | Specification |
|---|---|
| Target | |
| Alternative names | Aryl hydrocarbon receptor (Ah receptor, AhR)|Class E basic helix-loop-helix protein 76 (bHLHe76)|AHR|BHLHE76 |
| Gene ID | |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | aryl hydrocarbon receptor |
| Conjugate | |
| Molecular weight | |
| Purity | |
| Purification | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Scientific Background
Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes(such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.
Product Overview
This polyclonal antibody, raised in Rabbit, recognizes AHR. It is validated for ELISA, Western Blot, Immunohistochemistry, Immunoprecipitation.
Validated Applications
| Applications | ELISA, Western Blot, Immunohistochemistry, Immunoprecipitation |
|---|---|
| WB | 1:200-1:2000 |
| IP | 1:200-1:2000 |
| IHC | 1:20-1:200 |
Optimal dilutions should be determined by the end user for each application and sample type.
Immunogen
aryl hydrocarbon receptor
Specifications
| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse |
| Immunogen | aryl hydrocarbon receptor |
| Purification | Immunogen Affinity Purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Form | Liquid |
| Target MW | 105 kDa |
| UniProt # | P35869 |
| Gene ID | 196 |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Alternative Names | Aryl hydrocarbon receptor (Ah receptor, AhR)|Class E basic helix-loop-helix protein 76 (bHLHe76)|AHR|BHLHE76 |
Reactivity Notes
Validated reactivity: Human, Mouse. For other species, epitope conservation may allow cross-reactivity; confirm with appropriate controls.
Safety & Handling
This product is for research use only (RUO) and is not intended for diagnostic or therapeutic use. The formulation contains sodium azide; handle with standard laboratory precautions.
Related Products
Explore related antibodies and reagents for AHR research from Fine Test, or contact us for alternative formats.
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