Alaproclate hydrochloride

SKU:BHB21900889
Overview
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Alaproclate hydrochloride (CAS 60719-83-7) is an antagonist. Relevant to Neuronal Signaling and Membrane Transporter/Ion Channel research. Molecular formula C13H19Cl2NO2, molecular weight 292.20 g/mol. Also known as GEA 654 hydrochloride and A03 hydrochloride.
CAS Number 60719-83-7
Molecular Weight 292.20 g/mol
Storage See Certificate of Analysis
Options selector
Catalog no. Size
HY-133732-5MG 5 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 5 mg
  • Lead time: made to order; typically ships within 2–3 weeks.
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: store as stated on the Certificate of Analysis; contact us if you need the condition before ordering.
Field Specification
Alternative names GEA 654 hydrochloride; A03 hydrochloride
CAS no. 60719-83-7
Applications
  • Functional Assay (In Vitro)
Molecular weight 292.20
Molecular formula C13H19Cl2NO2
SMILES NC(C)C(OC(C)(C)CC1=CC=C(Cl)C=C1)=O.[H]Cl
Storage Refer to Certificate of Analysis (CoA) for storage conditions
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-133732
Main SKU BHB21900889
Antagonists

Compound Overview

Alaproclate hydrochloride, also known as GEA 654 hydrochloride or A03 hydrochloride, is a selective, orally active serotonin reuptake inhibitor (SSRI). It also acts as a potent, reversible, noncompetitive antagonist of NMDA receptor-coupled ion flow[1][2]. It has the molecular formula C13H19Cl2NO2 and a molecular weight of 292.20 g/mol.

Physical & Chemical Properties

CAS Number 60719-83-7
Molecular Formula C13H19Cl2NO2
Molecular Weight 292.20 g/mol
SMILES NC(C)C(OC(C)(C)CC1=CC=C(Cl)C=C1)=O.[H]Cl
Signaling Pathway Neuronal Signaling; Membrane Transporter/Ion Channel; GPCR/G Protein
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Campagna J, et al. A small molecule ApoE4-targeted therapeutic candidate that normalizes sirtuin 1 levels and improves cognition in an Alzheimer's disease mouse model. Sci Rep. 2018 Dec 4;8(1):17574.

[2]. Wilkinson A, et al. Alaproclate acts as a potent, reversible and noncompetitive antagonist of the NMDA receptor coupled ion flow.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.

Q.How long does this take to ship?
A.This item is produced on request and typically ships within 2–3 weeks.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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