| Field | Specification |
|---|---|
| Target | |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Recombinant protein of human ALDH6A1 |
| Conjugate | |
| Purification | |
| Concentration | |
| Storage | |
| Storage buffer | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Scientific Background
This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
Product Overview
This polyclonal antibody, raised in Rabbit, recognizes ALDH6A1. It is validated for Western Blot, Immunohistochemistry.
Validated Applications
| Applications | Western Blot, Immunohistochemistry |
|---|---|
| WB | 1:500-1:2000 |
| IHC | 1:50-1:200 |
Optimal dilutions should be determined by the end user for each application and sample type.
Immunogen
Recombinant protein of human ALDH6A1
Specifications
| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Recombinant protein of human ALDH6A1 |
| Purification | Affinity Purification |
| Concentration | 0.4 mg/mL |
| Storage Buffer | PBS with 0.05% sodium azide and 50% glycerol, pH 7.4 |
| Calculated MW | 58kDa |
| UniProt # | Q02252 |
| Lead Time | 2-3 business days |
| Validity | 12 months |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | Ice packs |
| Target Synonyms | 1110038I05Rik;AI314632;Aldehyde dehydrogenase 6 family member A1;Aldehyde dehydrogenase family 6 member A1;Aldehyde dehydrogenase family 6;subfamily A1;ALDH6A1;Malonate semialdehyde dehydrogenase;Malonate-semialdehyde dehydrogenase [acylating];Methylmalonate semialdehyde dehydrogenase [acylating] mitochondrial;Methylmalonate-semialdehyde dehydrogenase [acylating];MGC37325;MGC40271;Mitochondrial ac |
Reactivity Notes
Validated reactivity: Human, Mouse, Rat. For other species, epitope conservation may allow cross-reactivity; confirm with appropriate controls.
Safety & Handling
This product is for research use only (RUO) and is not intended for diagnostic or therapeutic use. The formulation contains sodium azide; handle with standard laboratory precautions.
Related Products
Explore related antibodies and reagents for ALDH6A1 research from Elabscience Biotechnology Co Ltd, or contact us for alternative formats.
Customization & Add-ons: Can't find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
