| Field | Specification |
|---|---|
| Alternative names | (-)-Altemicidin |
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C13H20N4O7S |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Altemicidin, also known as (-)-Altemicidin, is a monoterpene alkaloid first isolated from S. sioyaensis, with acaricidal and anticancer activities. In a greenhouse pot test, it proved acaricidal against two-spotted spider mites (T. urticae) at concentrations of 10 and 100 ppm. It also inhibits growth of murine L1210 lymphocytic leukemia and IMC carcinoma cells, with IC50 values of 0.84 and 0.82 μg/mL, respectively, while being toxic to mice, with an LD50 of 0.3 mg/kg. It has the molecular formula C13H20N4O7S and a molecular weight of 376.39 g/mol.
Physical & Chemical Properties
| CAS Number | 125399-82-8 |
|---|---|
| Molecular Formula | C13H20N4O7S |
| Molecular Weight | 376.39 g/mol |
| SMILES | O=C(C[S](N)(=O)=O)N[C@@]1([C@@](CN2C)([H])[C@@](C(C(N)=O)=C2)([H])C[C@@H]1O)C(O)=O |
| Signaling Pathway | Cancer |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
[1]. Takahashi, et al. Altemicidin, a new acaricidal and antitumor substance. I. Taxonomy, fermentation, isolation and physico-chemical and biological properties. J. Antibiot. (Tokyo) 42(11), 1556-1561 (1989).
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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