| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | 4-[(2-Amino-3,5-dibromobenzyl)amino]cyclohexanol |
| Cas No. | |
| Form | White Solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble to 50 mM in DMSO |
| Source | Synthetic |
| Storage |
Ambroxol HCl is a mucolytic agent with potent sodium channel-blocking activity and notable antioxidant and anti-inflammatory properties. In neuroscience, ambroxol has gained attention for its ability to enhance lysosomal function and promote the clearance of misfolded proteins, particularly glucocerebrosidase in Parkinson’s disease models. Its neuroprotective effects are attributed to improved autophagy, reduced neuroinflammation, and stabilization of neuronal ion channels. These mechanisms support its potential as a disease-modifying therapy in neurodegenerative disorders.
Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.
Safety Phrases:
- S22 - Do not breathe dust
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
- S45- In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)
Hazard Phrases:
H302
Ambroxol HCl (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-153)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
2. Sanderson R.J., et al. (1976) Respir Phys. 27: 379-392.
