| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C25H24ClNO9 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
AMPK-α1β1γ1 activator 1 (M1) is an acyl glucuronide metabolite of an indole-3-carboxylic acid-based AMPK activator. It can selectively activate the human β1 isoform with an EC50 of 38.1 nM and can bind directly to the human AMPK α1β1γ1 isoform, and can be used in diabetic nephropathy research[1]. It has the molecular formula C25H24ClNO9 and a molecular weight of 517.91 g/mol.
Physical & Chemical Properties
| CAS Number | 1943510-86-8 |
|---|---|
| Molecular Formula | C25H24ClNO9 |
| Molecular Weight | 517.91 g/mol |
| SMILES | OC([C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1OC(C2=CNC3=CC(Cl)=C(C4=CC=C(C5(CCC5)O)C=C4)C=C23)=O)=O |
| Signaling Pathway | Epigenetics; PI3K/Akt/mTOR |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Biological Activity
Activity & Target
EC50: 38.1 nM (AMPK-α1β1γ1)[1]
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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