| Field | Specification |
|---|---|
| Target | |
| Alternative names | 5-hydroxytryptamine receptor 7; 5-HT-7; 5-HT7; 5-HT-X; Serotonin receptor 7; HTR7 |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human 5HT7 Receptor |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 25H01 is a rabbit monoclonal antibody that recognizes 5-hydroxytryptamine receptor 7 (gene HTR7) in human, mouse and rat samples and is validated for Western blot. The predicted molecular weight is 53.6 kDa, and the supplier reports an observed band at about 54 kDa.
The serotonin 7 receptor (5-HT7, HTR7) is a G protein-coupled receptor that couples to Gs and stimulates adenylate cyclase to raise cAMP. It is found in the brain, including the thalamus and hypothalamus, and in smooth muscle, and it is studied in circadian rhythm, thermoregulation, sleep and mood regulation.
| Target | 5-hydroxytryptamine receptor 7 (gene HTR7; UniProt P34969, human) |
|---|---|
| Clone | 25H01 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 53.6 kDa |
| Observed MW | 54 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|
Immunogen
Synthetic peptide based on the sequence of human 5HT7 Receptor.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places 5-hydroxytryptamine receptor 7 in the cell membrane. Tissue expression noted by UniProt (human): Predominant isoform in spleen, caudate and hippocampus...
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
