| Field | Specification |
|---|---|
| Target | |
| Alternative names | Alpha-sarcoglycan;Alpha-SG;50 kDa dystrophin-associated glycoprotein;50DAG;Adhalin;Dystroglycan-2;SGCA;ADL, DAG2; |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human alpha Sarcoglycan |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone ABGE-19 is a rabbit monoclonal antibody that recognizes alpha-sarcoglycan (gene SGCA) in human, mouse and rat samples and is validated for Western blot, IHC and immunoprecipitation. The predicted molecular weight is 42.9 kDa, and the supplier reports an observed band at about 50 kDa.
Alpha-sarcoglycan (SGCA) is a transmembrane glycoprotein of the sarcoglycan complex in skeletal and cardiac muscle. This complex is part of the dystrophin-associated glycoprotein complex, which links the actin cytoskeleton to the extracellular matrix and protects the muscle membrane, and SGCA mutations cause limb-girdle muscular dystrophy.
| Target | Alpha-sarcoglycan (gene SGCA; UniProt Q16586, human) |
|---|---|
| Clone | ABGE-19 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 42.9 kDa |
| Observed MW | 50 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
| Immunoprecipitation | 1:40 |
Immunogen
Synthetic peptide based on the sequence of human alpha Sarcoglycan.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places alpha-sarcoglycan in the cell membrane and cytoplasm. Tissue expression noted by UniProt (human): Most strongly expressed in skeletal muscle.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
