| Field | Specification |
|---|---|
| Target | |
| Alternative names | APOBEC3C; APOBEC1L; PBI; DNA dC->dU-editing enzyme APOBEC-3C; A3C; EC 3.5.4.38; APOBEC1-like; Phorbolin I |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human APOBEC3C. |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody recognizes DNA dC->dU-editing enzyme APOBEC-3C (gene APOBEC3C) in human, mouse and rat samples and is validated for Western blot, IHC, ICC/IF and flow cytometry.
APOBEC3C is a cytidine deaminase of the APOBEC3 family that can edit cytosine to uracil in single-stranded DNA. It contributes to innate defense against retroviruses and retrotransposons and is studied, with other family members, in antiviral immunity and viral restriction.
| Target | DNA dC->dU-editing enzyme APOBEC-3C (gene APOBEC3C; UniProt Q9NRW3, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / Rabbit IgG |
| Reactivity | Human, Mouse, Rat |
| Purification | Immunogen affinity purified |
| Form | Lyophilized |
| Formulation | Per vial: 4 mg trehalose; 0.9 mg NaCl; 0.2 mg Na2HPO4 |
| Reconstitution | 500 µg/mL after adding 0.2 mL distilled water |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.25–0.5 µg/mL (Human, Mouse, Rat) |
|---|---|
| IHC (paraffin sections) | 2–5 µg/mL (Human) |
| Immunocytochemistry / Immunofluorescence | 5 µg/mL (Human) |
| Flow cytometry (fixed cells) | 1–3 µg/1×106 cells (Human) |
Conditions in the example images (IHC): heat-mediated antigen retrieval in EDTA buffer (pH 8.0).
Immunogen
Synthetic peptide from the N-terminal region of human APOBEC3C.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places DNA dC->dU-editing enzyme APOBEC-3C in the nucleus and cytoplasm. Tissue expression noted by UniProt (human): Expressed in spleen, testes, peripherical blood lymphocytes, heart, thymus, prostate and ovary.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
