| Field | Specification |
|---|---|
| Target | |
| Alternative names | ATP7A; MC1; MNK; Copper-transporting ATPase 1; EC 7.2.2.8; Copper pump 1; Menkes disease-associated protein |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human ATP7A, which shares |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody recognizes copper-transporting ATPase 1 (gene ATP7A) in human samples and is validated for Western blot.
ATP7A is a copper-transporting P-type ATPase that moves copper into the secretory pathway for loading onto copper-dependent enzymes and pumps excess copper out of cells. It is needed for intestinal copper absorption, and mutations cause Menkes disease.
| Target | Copper-transporting ATPase 1 (gene ATP7A; UniProt Q04656, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / Rabbit IgG |
| Reactivity | Human |
| Purification | Immunogen affinity purified |
| Form | Lyophilized |
| Formulation | Per vial: 4 mg trehalose; 0.9 mg NaCl; 0.2 mg Na2HPO4 |
| Reconstitution | 500 µg/mL after adding 0.2 mL distilled water |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.25–0.5 µg/mL (Human) |
|---|
Immunogen
Synthetic peptide from the C-terminal region of human ATP7A.
Reactivity Notes
The supplier lists reactivity with human. UniProt places copper-transporting ATPase 1 in the cell membrane, melanosome membrane, early endosome membrane and cell projection. Tissue expression noted by UniProt (human): Widely expressed including in heart, brain, lung, muscle, kidney, pancreas, and to a lesser extent placenta.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
