| Field | Specification |
|---|---|
| Target | |
| Alternative names | BBS1; BBS2L2; Bardet-Biedl syndrome 1 protein; BBS2-like protein 2 |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | E.coli-derived human ATF5 recombinant protein (Position: L11-R275). Human ATF5 shares 86.5% and 87.2% amino acid (aa) sequence identity with mouse and rat ATF5, respectively. |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody recognizes BBSome complex member BBS1 in human, mouse and rat samples and is validated for Western blot and ELISA.
BBS1 is a core subunit of the BBSome, a protein complex that traffics specific membrane proteins, such as certain G protein-coupled receptors, into and out of primary cilia. Mutations in BBS1 are a common cause of Bardet–Biedl syndrome, a ciliopathy with retinal degeneration, obesity and polydactyly.
| Target | BBSome complex member BBS1 (gene BBS1; UniProt Q8NFJ9, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / Rabbit IgG |
| Reactivity | Human, Mouse, Rat |
| Purification | Immunogen affinity purified |
| Form | Lyophilized |
| Formulation | Per vial: 4 mg trehalose; 0.9 mg NaCl; 0.2 mg Na2HPO4 |
| Reconstitution | 500 µg/mL after adding 0.2 mL distilled water |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.25–0.5 µg/mL (Mouse, Rat) |
|---|---|
| ELISA | 0.1–0.5 µg/mL (Human) |
Immunogen
Recombinant human ATF5 fragment (Leu11–Arg275), expressed in E. coli. Sequence identity with the mouse and rat orthologs: 86.5% and 87.2%, respectively.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places BBSome complex member BBS1 in the cell projection and cytoplasm. Tissue expression noted by UniProt (human): Highly expressed in the kidney.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
