| Field | Specification |
|---|---|
| Target | |
| Alternative names | Beta-2 adrenergic receptor;Beta-2 adrenoreceptor;Beta-2 adrenoceptor;ADRB2;ADRB2R, B2AR; |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human beta 2 Adrenergic Receptor |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone AE-1 is a rabbit monoclonal antibody that recognizes beta-2 adrenergic receptor (gene ADRB2) in human, mouse and rat samples and is validated for Western blot, IHC and immunoprecipitation. The predicted molecular weight is 46.5 kDa, and the supplier reports an observed band at about 62 kDa.
Beta-2 adrenergic receptor (ADRB2) is a G protein-coupled receptor for epinephrine that relaxes smooth muscle in the airways and blood vessels. It is the target of asthma bronchodilators and has been a key model receptor for GPCR structure and signaling.
| Target | Beta-2 adrenergic receptor (gene ADRB2; UniProt P07550, human) |
|---|---|
| Clone | AE-1 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 46.5 kDa |
| Observed MW | 62 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
| Immunoprecipitation | 1:30 |
Samples with a confirmed band (WB): A431 cells.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human beta 2 Adrenergic Receptor.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places beta-2 adrenergic receptor in the cell membrane and Golgi apparatus. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
