| Field | Specification |
|---|---|
| Target | |
| Alternative names | Beta-defensin 1; BD-1; hBD-1; Defensin, beta 1; DEFB1; BD1; HBD1 |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human beta Defensin 1 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 20D19 is a rabbit monoclonal antibody that recognizes beta-defensin 1 (gene DEFB1) in human samples and is validated for Western blot. The predicted molecular weight is 7.4 kDa, and the supplier reports an observed band at about 7 kDa.
Human β-defensin 1 (hBD-1, encoded by DEFB1) is an antimicrobial peptide that is constantly produced by epithelial cells of the skin, airways, urogenital tract and kidney. It kills bacteria and can bind the chemokine receptor CCR6, linking innate and adaptive immunity. It has also been reported to support sperm motility. hBD-1 is studied in mucosal host defense.
| Target | Beta-defensin 1 (gene DEFB1; UniProt P60022, human) |
|---|---|
| Clone | 20D19 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 7.4 kDa |
| Observed MW | 7 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|
Immunogen
Synthetic peptide based on the sequence of human beta Defensin 1.
Reactivity Notes
The supplier lists reactivity with human. UniProt describes beta-defensin 1 as secreted and also located in the membrane. Tissue expression noted by UniProt (human): Blood plasma.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
