| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Microtubule-associated proteins 1A/1B light chain 3A;Autophagy-related protein LC3 A;Autophagy-related ubiquitin-like modifier LC3 A;MAP1 light chain 3-like protein 1;MAP1A/MAP1B light chain 3 A;MAP1A/MAP1B LC3 A;Microtubule-associated protein 1 light chain 3 alpha;MAP1LC3A; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | A synthesized peptide derived from human BIN1 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-BIN1 Rabbit Monoclonal Antibody catalog # M01551-3. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse.
Protein: Glycogen synthase kinase-3 beta (gsk3b) | Gene: Microtubule-associated proteins 1A/1B light chain 3A | Target: BIN1 | Function: Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes) (PubMed:20713600, PubMed:24290141). Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (PubMed:20713600). . | Research areas: Metabolism,Pathways and Processes,Apoptosis,Cancer,Cell Biology,Intracellular,Cell Death,Metabolism Processes,Invasion/Microenvironment,Apoptotic Markers
Host: Rabbit | Clonality/Clone: Monoclonal / Clone: 30B92 | Isotype: IgG | Reactivity: Human,Mouse | Immunogen: A synthesized peptide derived from human BIN1 | Concentration: 0.5mg/ml | Purification: Affinity-chromatography
Applications: WB, IHC, IF, ICC, FC
Observed MW: 65-80 kDa | Calculated MW: 14272 MW
Cellular localization: Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Cytoplasmic vesicle, autophagosome . LC3-II binds to the autophagic membranes.
Tissue details: Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes. .
Status: Active
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