| Field | Specification |
|---|---|
| Target | |
| Alternative names | Bone morphogenetic protein 2;BMP-2;Bone morphogenetic protein 2A;BMP-2A;BMP2;BMP2A; |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human BMP2 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone AOHD-2 is a rabbit monoclonal antibody that recognizes bone morphogenetic protein 2 (gene BMP2) in human and mouse samples and is validated for Western blot. The predicted molecular weight is 44.7 kDa, and the supplier reports an observed band at about 38 kDa.
Bone morphogenetic protein 2 (BMP2) is a TGF-β superfamily growth factor that binds type I and type II BMP receptors and activates SMAD1/5/8 signaling. It is a strong inducer of bone and cartilage formation and also shapes heart, neural and limb development, which makes it a standard factor in osteogenesis and developmental biology research.
| Target | Bone morphogenetic protein 2 (gene BMP2; UniProt P12643, human) |
|---|---|
| Clone | AOHD-2 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human, Mouse |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 44.7 kDa |
| Observed MW | 38 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|
Samples with a confirmed band (WB): HeLa cells.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human BMP2.
Reactivity Notes
The supplier lists reactivity with human and mouse. UniProt describes bone morphogenetic protein 2 as a secreted protein. Tissue expression noted by UniProt (human): Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
Xu Bin et al. (2026) An injectable multi-functional strontium based gentiopicroside hydrogel accelerates bone regeneration via immunomodulation and promoting osteo-/angiogenesis effects. Advanced Composites and Hybrid Materials. 10.1007/s42114-026-01719-5
Yang Zhu et al. (2026) Size-Dependent Layered Double Hydroxide Nanoparticles Promote Osteogenesis and Bone Regeneration via METTL3-Dependent N6-Methyladenosine Modification of Runx2 mRNA. International Journal of Nanomedicine. 10.2147/IJN.S611081
Chao Shan et al. (2024) Network pharmacological study and in vitro studies validation-Molecular dynamics simulation of Cistanche deserticola in promoting periodontitis and bone remodeling. International Immunopharmacology. 10.1016/j.intimp.2024.112299
Jian Cong-Xiang et al. (2017) Effects of rhBMP-2 gene transfection to periodontal ligament cells on osteogenesis. Bioscience Reports. 10.1042/BSR20160585
Fang Liu et al. (2010) Effect of high glucose levels on the calcification of vascular smooth muscle cells by inducing osteoblastic differentiation and intracellular calcium deposition via BMP-2/Cbfα-1 pathway. Journal of Zhejiang University-SCIENCE B. 10.1631/jzus.B1000119
