| Field | Specification |
|---|---|
| Target | |
| Alternative names | Caveolin-3;M-caveolin;CAV3; |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human Caveolin-3 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone FE-3 is a rabbit monoclonal antibody that recognizes caveolin-3 (gene CAV3) in human, mouse and rat samples and is validated for Western blot and immunoprecipitation. The predicted molecular weight is 17.3 kDa, and the supplier reports an observed band at about 17 kDa.
Caveolin-3 (CAV3) is the muscle-specific caveolin that forms caveolae in skeletal and cardiac muscle cells. It organizes signaling molecules and ion channels at the sarcolemma and supports membrane repair together with dysferlin. Mutations in CAV3 cause caveolinopathies, including a form of limb-girdle muscular dystrophy and rippling muscle disease.
| Target | Caveolin-3 (gene CAV3; UniProt P56539, human) |
|---|---|
| Clone | FE-3 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 17.3 kDa |
| Observed MW | 17 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunoprecipitation | 1:20 |
Immunogen
Synthetic peptide based on the sequence of human caveolin-3.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places caveolin-3 in the Golgi apparatus membrane, cell membrane and membrane. Tissue expression noted by UniProt (human): Expressed predominantly in muscle.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
