| Field | Specification |
|---|---|
| Target | |
| Alternative names | C-C motif chemokine 21; 6Ckine; Beta-chemokine exodus-2; Secondary lymphoid-tissue chemokine; SLC; Small-inducible cytokine A21; CCL21; SCYA21 |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human CCL21 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 24C85 is a rabbit monoclonal antibody that recognizes C-C motif chemokine 21 (gene CCL21) in human samples and is validated for Western blot. The predicted molecular weight is 14.6 kDa, and the supplier reports an observed band at about 15 kDa.
CCL21 (also called SLC or 6Ckine) is a C-C chemokine produced in lymphatic vessels and lymph node T-cell zones. It binds CCR7 and guides naive T cells and mature dendritic cells into lymph nodes, and it also binds the atypical receptor ACKR4. Its extended, positively charged C-terminal tail anchors it to extracellular matrix.
| Target | C-C motif chemokine 21 (gene CCL21; UniProt O00585, human) |
|---|---|
| Clone | 24C85 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 14.6 kDa |
| Observed MW | 15 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|
Immunogen
Synthetic peptide based on the sequence of human CCL21.
Reactivity Notes
The supplier lists reactivity with human. UniProt describes C-C motif chemokine 21 as a secreted protein. Tissue expression noted by UniProt (human): Highly expressed in high endothelial venules of lymph nodes, spleen and appendix.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
