| Field | Specification |
|---|---|
| Target | |
| Alternative names | Tumor necrosis factor receptor superfamily member 4;OX40 antigen;OX40L receptor;CD134;Tnfrsf4;Ox40, Txgp1; |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of mouse CD134. |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody detects tumor necrosis factor receptor superfamily member 4 (gene Tnfrsf4) in mouse samples and is validated for Western blot. The predicted molecular weight is 30.2 kDa, and the supplier reports an observed band at about 60 kDa.
OX40 (TNFRSF4, CD134) is a costimulatory receptor expressed on activated T cells that binds OX40 ligand (TNFSF4). Its signals support T-cell survival, expansion and the formation of long-lived memory, so OX40 is widely studied in adaptive immunity, autoimmunity and cancer immunotherapy research. It also serves as an entry receptor for human herpesvirus 6B.
| Target | Tumor necrosis factor receptor superfamily member 4 (gene Tnfrsf4; UniProt P47741, mouse) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / Rabbit IgG |
| Reactivity | Mouse |
| Form | Lyophilized |
| Formulation | Per vial: 0.9 mg NaCl; 0.2 mg Na2HPO4; 0.05 mg thimerosal; 0.05 mg NaN3; plus stabilizers |
| Calculated MW | 30.2 kDa |
| Observed MW | 60 kDa |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.1–0.5 µg/mL (Mouse) |
|---|
Samples with a confirmed band (WB): mouse brain tissue, mouse spleen tissue, mouse liver tissue.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide from the N-terminal region of mouse CD134.
Reactivity Notes
The supplier lists reactivity with mouse. UniProt places tumor necrosis factor receptor superfamily member 4 in the membrane. Tissue expression noted by UniProt (mouse): Expressed in CD4(+) T-cells and in T-helper Th17 cells (at protein level). The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
