| Field | Specification |
|---|---|
| Target | |
| Alternative names | Low affinity immunoglobulin epsilon Fc receptor; BLAST-2; C-type lectin domain family 4 member J; Fc-epsilon-RII; Immunoglobulin E-binding factor; Lymphocyte IgE receptor; CD antigen CD23; FCER2; CD23A; CLEC4J; FCE2; IGEBF |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human CD23. |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone ADIC-6 is a rabbit monoclonal antibody that recognizes low affinity immunoglobulin epsilon Fc receptor (gene FCER2) in human samples and is validated for Western blot, IHC and flow cytometry. The predicted molecular weight is 36.5 kDa, and the supplier reports an observed band at about 36 kDa.
FcεRII (FCER2, CD23) is a low-affinity receptor for IgE and a C-type lectin that also binds CR2 (CD21). It is found on B cells and other immune cells, where it helps regulate IgE production and IgE-dependent antigen uptake and presentation. CD23 is studied in allergy, B-cell biology and chronic lymphocytic leukemia.
| Target | Low affinity immunoglobulin epsilon Fc receptor (gene FCER2; UniProt P06734, human) |
|---|---|
| Clone | ADIC-6 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 36.5 kDa |
| Observed MW | 36 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
| Flow cytometry | 1:30 |
Samples with a confirmed band (WB): Raji cells.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human CD23.
Reactivity Notes
The supplier lists reactivity with human. UniProt describes low affinity immunoglobulin epsilon Fc receptor as secreted and also located in the cell membrane. Tissue expression noted by UniProt (human): Detected in urine (at protein level). The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
