| Field | Specification |
|---|---|
| Target | |
| Alternative names | Platelet glycoprotein Ib alpha chain; GP-Ib alpha; GPIb-alpha; GPIbA; Glycoprotein Ibalpha; Antigen CD42b-alpha; CD antigen CD42b; GP1BA |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human CD42b |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 17G60 is a rabbit monoclonal antibody that recognizes platelet glycoprotein Ib alpha chain (gene GP1BA) in human samples and is validated for Western blot and IHC. The predicted molecular weight is 71.5 kDa, and the supplier reports an observed band at about 143 kDa.
Glycoprotein Ib alpha (GP1BA) is the ligand-binding subunit of the platelet GPIb-IX-V complex. It binds von Willebrand factor on exposed subendothelium, allowing platelets to tether under high shear flow, and its defects cause Bernard-Soulier syndrome, so it is central to studies of platelet adhesion and hemostasis.
| Target | Platelet glycoprotein Ib alpha chain (gene GP1BA; UniProt P07359, human) |
|---|---|
| Clone | 17G60 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 71.5 kDa |
| Observed MW | 143 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
Samples with a confirmed band (WB): human spleen.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human CD42b.
Reactivity Notes
The supplier lists reactivity with human. UniProt places platelet glycoprotein Ib alpha chain in the membrane. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
