| Field | Specification |
|---|---|
| Target | |
| Alternative names | Macrosialin;Gp110;CD68;CD68; |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human CD68 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone GBE-3 is a rabbit monoclonal antibody that recognizes macrosialin (gene CD68) in human, mouse and rat samples and is validated for Western blot. The predicted molecular weight is 37.4 kDa, and the supplier reports an observed band at about 37 kDa.
CD68 (macrosialin in mouse) is a heavily glycosylated protein located mainly in late endosomes and lysosomes of monocytes and macrophages. It is thought to take part in phagocytic and lysosomal activity, and it is one of the most widely used markers for macrophages in tissue sections.
| Target | Macrosialin (gene CD68; UniProt P34810, human) |
|---|---|
| Clone | GBE-3 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 37.4 kDa |
| Observed MW | 37 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|
Immunogen
Synthetic peptide based on the sequence of human CD68.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. Tissue expression noted by UniProt (human): Highly expressed by blood monocytes and tissue macrophages.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
Xiaobo Yu et al. (2025) Porcine pericardium crosslinked with POSS-PEG-CHO possesses weakened immunogenicity and anti-calcification property. Materials Today Bio. 10.1016/j.mtbio.2025.101677
Jinfeng Liu et al. (2016) Blockage of Galectin-receptor Interactions by α-lactose Exacerbates Plasmodium berghei-induced Pulmonary Immunopathology. Scientific Reports. 10.1038/srep32024
