| Field | Specification |
|---|---|
| Target | |
| Alternative names | Cell division cycle protein 16 homolog;Anaphase-promoting complex subunit 6;APC6;CDC16 homolog;CDC16Hs;Cyclosome subunit 6;CDC16;ANAPC6; |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human Cdc16/APC6 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone IOI-3 is a rabbit monoclonal antibody that recognizes cell division cycle protein 16 homolog (gene CDC16) in human, mouse and rat samples and is validated for Western blot and ICC/IF. The predicted molecular weight is 71.7 kDa; the supplier reports observed bands at 60, 66, 72 kDa.
CDC16 is a core subunit of the anaphase-promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that targets cell cycle regulators such as securin and mitotic cyclins for degradation. APC/C activity drives the metaphase-to-anaphase transition and mitotic exit, so CDC16 is studied in mitosis and genome stability.
| Target | Cell division cycle protein 16 homolog (gene CDC16; UniProt Q13042, human) |
|---|---|
| Clone | IOI-3 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 71.7 kDa |
| Observed MW | 60, 66, 72 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunocytochemistry / Immunofluorescence | 1:50–1:200 |
Immunogen
Synthetic peptide based on the sequence of human cdc16/APC6.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places cell division cycle protein 16 homolog in the cytoplasm.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
