| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Myocyte-specific enhancer factor 2C;MEF2C; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | A synthesized peptide derived from human CFD |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-CFD Rabbit Monoclonal Antibody catalog # M01134. Tested in WB application. This antibody reacts with Human.
Protein: Glycogen synthase kinase-3 beta (gsk3b) | Gene: Myocyte-specific enhancer factor 2C | Target: CFD | Function: Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle- specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells. May also be involved in neurogenesis and in the development of cortical architecture (By similarity). Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2. . | Research areas: Calcium Signaling,Calmodulin Pathway,Cardiogenesis,Cardiovascular,Developmental Families,Domain Families,Epigenetics and Nuclear Signaling,Hypertrophy,Mesenchymal Stem Cells,Neurogenesis,Neurology Process,Neuroscience,Signal Transduction,Signaling Pathway,Stem Cells,Transcription,Transcription Factors,Transcription Factors/Regulators
Host: Rabbit | Clonality/Clone: Monoclonal / Clone: 30C23 | Isotype: IgG | Reactivity: Human | Immunogen: A synthesized peptide derived from human CFD | Concentration: 0.5mg/ml | Purification: Affinity-chromatography
Applications: WB
Observed MW: 25 kDa | Calculated MW: 51221 MW
Cellular localization: Nucleus.
Tissue details: Expressed in brain and skeletal muscle. .
Status: Active
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