| Field | Specification |
|---|---|
| Target | |
| Alternative names | Contactin-associated protein-like 2; Cell recognition molecule Caspr2; CNTNAP2; CASPR2; KIAA0868 |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human CNTP2 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 26C10 is a rabbit monoclonal antibody that recognizes contactin-associated protein-like 2 (gene CNTNAP2) in human, mouse and rat samples and is validated for Western blot and IHC. The predicted molecular weight is 148.2 kDa, and the supplier reports an observed band at about 160 kDa.
CASPR2 (CNTNAP2) is a neurexin-family transmembrane protein that, with contactin-2, clusters voltage-gated potassium channels at the juxtaparanodes of myelinated axons. It also plays roles in neuronal migration and synapse function, and it is widely studied in neurodevelopment and in genetic studies of autism spectrum disorders.
| Target | Contactin-associated protein-like 2 (gene CNTNAP2; UniProt Q9UHC6, human) |
|---|---|
| Clone | 26C10 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 148.2 kDa |
| Observed MW | 160 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
Immunogen
Synthetic peptide based on the sequence of human CNTP2.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places contactin-associated protein-like 2 in the membrane and cell projection. Tissue expression noted by UniProt (human): Predominantly expressed in nervous system.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
Weihua Liang et al. (2017) Alterations of Caspr2 and Nav1.6 on myelinated axon damage in a rat model of chronic cerebral hypoperfusion. Experimental and Therapeutic Medicine. 10.3892/etm.2017.4228
