| Field | Specification |
|---|---|
| Target | |
| Alternative names | Dihydropyrimidinase-related protein 1; DRP-1; Collapsin response mediator protein 1; CRMP-1; Inactive dihydropyrimidinase; Unc-33-like phosphoprotein 3; ULIP-3; CRMP1; DPYSL1; ULIP3 |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human CRMP1 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 18C29 is a rabbit monoclonal antibody that recognizes dihydropyrimidinase-related protein 1 (gene CRMP1) in human, mouse and rat samples and is validated for Western blot, IHC, ICC/IF, immunoprecipitation and flow cytometry. The predicted molecular weight is 62.2 kDa, and the supplier reports an observed band at about 62 kDa.
CRMP1 is a member of the collapsin response mediator protein family, cytosolic phosphoproteins abundant in the developing nervous system. It relays class 3 semaphorin signals to the cytoskeleton, contributing to growth cone collapse, axon guidance and neuronal migration.
| Target | Dihydropyrimidinase-related protein 1 (gene CRMP1; UniProt Q14194, human) |
|---|---|
| Clone | 18C29 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 62.2 kDa |
| Observed MW | 62 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
| Immunocytochemistry / Immunofluorescence | 1:50–1:200 |
| Immunoprecipitation | 1:40 |
| Flow cytometry | 1:30 |
Immunogen
Synthetic peptide based on the sequence of human CRMP1.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places dihydropyrimidinase-related protein 1 in the cytoplasm, cell projection and perikaryon. Tissue expression noted by UniProt (human): Brain.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
Luo Jing et al. (2012) Down-Regulation of CRMP-1 in Patients with Epilepsy and a Rat Model. Neurochemical Research. 10.1007/s11064-012-0712-6
