| Field | Specification |
|---|---|
| Target | |
| Alternative names | Casein kinase I isoform alpha; CKI-alpha; CK1; CSNK1A1 |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human CSNK1A1 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 24C02 is a rabbit monoclonal antibody that recognizes casein kinase I isoform alpha (gene CSNK1A1) in human, mouse and rat samples and is validated for Western blot. The predicted molecular weight is 38.9 kDa, and the supplier reports an observed band at about 35 kDa.
Casein kinase 1 alpha (CK1α, CSNK1A1) is a serine/threonine kinase with many substrates. In the Wnt pathway it primes β-catenin by phosphorylating Ser45, marking it for further phosphorylation by GSK3B and degradation. It also influences mTOR signaling, the NLRP3 inflammasome and circadian proteins, and is studied in Wnt biology and hematologic cancers.
| Target | Casein kinase I isoform alpha (gene CSNK1A1; UniProt P48729, human) |
|---|---|
| Clone | 24C02 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 38.9 kDa |
| Observed MW | 35 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|
Immunogen
Synthetic peptide based on the sequence of human CSNK1A1.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places casein kinase I isoform alpha in the cytoplasm, chromosome and nucleus speckle.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
