| Field | Specification |
|---|---|
| Target | |
| Alternative names | Catenin alpha-3; Alpha T-catenin; Cadherin-associated protein; CTNNA3 |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human CTNNA3 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 26C28 is a rabbit monoclonal antibody that recognizes catenin alpha-3 (gene CTNNA3) in human, mouse and rat samples and is validated for Western blot, IHC and immunoprecipitation. The predicted molecular weight is 99.8 kDa, and the supplier reports an observed band at about 100 kDa.
Alpha-T-catenin (CTNNA3) is an alpha-catenin family member expressed mainly in heart and testis. At the intercalated discs of cardiomyocytes it joins cadherin-catenin complexes to the cytoskeleton and is thought to help form stretch-resistant adhesion junctions, so it is studied in cardiac adhesion and cardiomyopathy research.
| Target | Catenin alpha-3 (gene CTNNA3; UniProt Q9UI47, human) |
|---|---|
| Clone | 26C28 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 99.8 kDa |
| Observed MW | 100 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
| Immunoprecipitation | 1:50 |
Samples with a confirmed band (WB): 293 cells.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human CTNNA3.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places catenin alpha-3 in the cytoplasm and cell junction. Tissue expression noted by UniProt (human): Predominantly expressed in heart and testis. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
