| Field | Specification |
|---|---|
| Target | |
| Alternative names | CTP synthase 1; CTP synthetase 1; Protein-asparagine deamidase CTPS1; UTP--ammonia ligase 1; CTPS1; CTPS |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human CTP synthase / CTPS |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 29C09 is a rabbit monoclonal antibody that recognizes CTP synthase 1 (gene CTPS1) in human and mouse samples and is validated for Western blot and flow cytometry. The predicted molecular weight is 66.7 kDa, and the supplier reports an observed band at about 72 kDa.
CTP synthase 1 (CTPS1) makes CTP from UTP, using ATP and glutamine as the nitrogen source, in the de novo pathway that supplies nucleotides for DNA, RNA and phospholipid synthesis. Activated lymphocytes depend heavily on CTPS1 to proliferate, and its loss causes immunodeficiency, so it is studied in lymphocyte metabolism and immunity.
| Target | CTP synthase 1 (gene CTPS1; UniProt P17812, human) |
|---|---|
| Clone | 29C09 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human, Mouse |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 66.7 kDa |
| Observed MW | 72 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Flow cytometry | 1:50 |
Samples with a confirmed band (WB): HeLa cells.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human CTP synthase / CTPS.
Reactivity Notes
The supplier lists reactivity with human and mouse. UniProt places CTP synthase 1 in the cytoplasm, nucleus and chromosome. Tissue expression noted by UniProt (human): Widely expressed at low level, except in activated T-cells where it is highly expressed. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
