| Field | Specification |
|---|---|
| Target | |
| Alternative names | CTRC; CLCR; Chymotrypsin-C; EC 3.4.21.2; Caldecrin |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human CTRC, which shares 86.4% amino acid (aa) sequence identity with both mouse and rat CTRC. |
| Purification | |
| Reconstitution | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody recognizes chymotrypsin-C (gene CTRC) in human and rat samples and is validated for Western blot and IHC.
Chymotrypsin C (CTRC) is a pancreatic serine protease secreted as an inactive precursor. By cutting trypsinogens and procarboxypeptidases at selected sites, it controls both their activation and their breakdown, helping protect the pancreas from premature trypsin activity. Variants in CTRC are linked to chronic pancreatitis, so it is studied in pancreatic physiology and disease.
| Target | Chymotrypsin-C (gene CTRC; UniProt Q99895, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / Rabbit IgG |
| Reactivity | Human, Rat |
| Purification | Immunogen affinity purified |
| Form | Lyophilized |
| Formulation | Per vial: 4 mg trehalose; 0.9 mg NaCl; 0.2 mg Na2HPO4 |
| Reconstitution | 500 µg/mL after adding 0.2 mL distilled water |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.25–0.5 µg/mL (Human, Rat) |
|---|---|
| IHC (paraffin sections) | 2–5 µg/mL (Rat) |
Conditions in the example images (IHC): heat-mediated antigen retrieval in EDTA buffer (pH 8.0).
Immunogen
Synthetic peptide from the C-terminal region of human CTRC. Sequence identity with the mouse and rat orthologs: 86.4%.
Reactivity Notes
The supplier lists reactivity with human and rat. Tissue expression noted by UniProt (human): Pancreas.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
