| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Cyclin-H;MO15-associated protein;p34;p37;CCNH; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Gene ID | |
| Host | |
| Immunogen | A synthesized peptide derived from human Cyclin H/p34 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-Cyclin H/p34 Rabbit Monoclonal Antibody catalog # M03013-3. Tested in WB application. This antibody reacts with Human, Mouse, Rat.
Protein: T-cell surface glycoprotein CD3 zeta chain | Gene: Cyclin-H | Target: CCNH | Function: Regulates CDK7, the catalytic subunit of the CDK- activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle. . | Research areas: Cell Biology,Cell Cycle,Epigenetics and Nuclear Signaling
Host: Rabbit | Clonality/Clone: Monoclonal / Clone: 28C49 | Isotype: IgG | Reactivity: Human,Mouse,Rat | Immunogen: A synthesized peptide derived from human Cyclin H/p34 | Concentration: 0.5mg/ml | Purification: Affinity-chromatography
Applications: WB
Observed MW: 35 kDa | Calculated MW: 37643 MW
Cellular localization: Nucleus.
Tissue details: Activated T-lymphocytes.
Status: Active
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