| Field | Specification |
|---|---|
| Alternative Names | Caldesmon;CDM;CALD1;CAD, CDM; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Gene ID | |
| Host | |
| Immunogen | A synthesized peptide derived from human CYFIP1 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-CYFIP1 Rabbit Monoclonal Antibody catalog # M04596. Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Protein: T-cell surface glycoprotein CD3 zeta chain | Gene: Caldesmon | Target: CYFIP1 | Function: Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also play an essential role during cellular mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration (By similarity). . | Research areas: DNA/RNA,Epigenetics and Nuclear Signaling,RNA Processing
Host: Rabbit | Clonality/Clone: Monoclonal / Clone: 29C25 | Isotype: IgG | Reactivity: Human,Mouse,Rat | Immunogen: A synthesized peptide derived from human CYFIP1 | Concentration: 0.5mg/ml | Purification: Affinity-chromatography
Applications: WB, IF, ICC, FC
Observed MW: 145 kDa | Calculated MW: 93231 MW
Cellular localization: Cytoplasm, cytoskeleton . Cytoplasm, myofibril . On thin filaments in smooth muscle and on stress fibers in fibroblasts (nonmuscle). .
Tissue details: High-molecular-weight caldesmon (isoform 1) is predominantly expressed in smooth muscles, whereas low-molecular- weight caldesmon (isoforms 2, 3, 4 and 5) are widely distributed in non-muscle tissues and cells. Not expressed in skeletal muscle or heart.
Status: Active
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