| Field | Specification |
|---|---|
| Target | |
| Alternative names | Catenin delta-1;Cadherin-associated Src substrate;CAS;p120 catenin;p120 (ctn);p120 (cas);CTNND1;KIAA0384; |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human delta 1 Catenin/p120 Catenin |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone GI-3 is a rabbit monoclonal antibody that recognizes catenin delta-1 (gene CTNND1) in human, mouse and rat samples and is validated for Western blot, IHC, ICC/IF and immunoprecipitation. The predicted molecular weight is 108.2 kDa, and the supplier reports an observed band at about 105 kDa.
p120-catenin (CTNND1) binds the juxtamembrane region of classical cadherins such as E- and N-cadherin and prevents their endocytosis, keeping adherens junctions stable. It also regulates Rho family GTPases and the transcription factor Kaiso, and it is a substrate of SRC and several receptor tyrosine kinases. It is studied in epithelial adhesion, cell migration and cancer.
| Target | Catenin delta-1 (gene CTNND1; UniProt O60716, human) |
|---|---|
| Clone | GI-3 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 108.2 kDa |
| Observed MW | 105 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
| Immunocytochemistry / Immunofluorescence | 1:50–1:200 |
| Immunoprecipitation | 1:30 |
Samples with confirmed staining (ICC/IF): MCF-7 cells.
Immunogen
Synthetic peptide based on the sequence of human delta 1 Catenin/p120 Catenin.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places catenin delta-1 in the cell junction, cytoplasm, nucleus and cell membrane. Tissue expression noted by UniProt (human): Expressed in vascular endothelium. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
