| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Segment polarity protein dishevelled homolog DVL-3;Dishevelled-3;DSH homolog 3;DVL3;KIAA0208; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | A synthetic peptide corresponding to a sequence in the middle region of human Dishevelled 3, identical to the related mouse sequence. |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Overview
This antibody is intended for detection of DVL3 (Segment polarity protein dishevelled homolog DVL-3) in biological samples using common immunoassay formats. It is typically selected based on target identity, species reactivity, clonality/clone information, and detection modality.
Vendor notes: Boster Bio Anti-Dishevelled 3/DVL3 Antibody Picoband® catalog # A03577. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key elements and design rationale
- Antibody format: Rabbit Polyclonal Rabbit IgG
- Immunogen / epitope context: A synthetic peptide corresponding to a sequence in the middle region of human Dishevelled 3, identical to the related mouse sequence.
- Molecular weight context: reported MW: 78 kDa; calculated MW: 78055 MW
- Reactivity: Human,Mouse,Rat
- Applications: WB
As a polyclonal antibody, the reagent recognizes multiple epitopes on the target, which can improve detection robustness but may increase sensitivity to sample-dependent epitope changes.
Biological background
Segment polarity protein dishevelled homolog DVL-3; Segment polarity protein dishevelled homolog DVL-3. Segment polarity protein dishevelled homolog DVL-3 is a protein that in humans is encoded by the DVL3 gene. It is mapped to 3q27.1. This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation. Functional note: May play a role in the signal transduction pathway mediated by multiple Wnt genes. Reported localization: Cytoplasm .
Research relevance and current trends
- Cardiogenesis: Researchers commonly examine how DVL3 (Segment polarity protein dishevelled homolog DVL-3) relates to this theme using model systems and orthogonal readouts.
- Cardiovascular: Researchers commonly examine how DVL3 (Segment polarity protein dishevelled homolog DVL-3) relates to this theme using model systems and orthogonal readouts.
- Neurogenesis: Researchers commonly examine how DVL3 (Segment polarity protein dishevelled homolog DVL-3) relates to this theme using model systems and orthogonal readouts.
Common research applications
- Western blotting: compare relative DVL3 (Segment polarity protein dishevelled homolog DVL-3) levels across conditions; band patterns may reflect isoforms and processing.
Notes for experimental interpretation
- Specificity notes: No cross reactivity with other proteins.
- Cross-reactivity: No cross-reactivity with other proteins.
- Isoforms and PTMs: Apparent size and signal patterns can differ across splice isoforms, proteolytic processing, and post-translational modifications.
- Controls: Include an isotype control (as relevant), no-primary control for imaging, and orthogonal validation such as KD/KO samples when available.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
