| Field | Specification |
|---|---|
| Target | |
| Alternative names | DNA (cytosine-5)-methyltransferase 3-like, DNMT3L |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Applications | |
| Purity | |
| Purification | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Storage buffer | |
| Catalog no. (Mfr.) | |
| Main SKU |
Overview
Antibody against DNMT3L (DNA (cytosine-5)-methyltransferase 3-like) for research detection of protein expression and localization.
Target biology
DNMT3L is commonly studied as part of epigenetic and chromatin-regulatory machinery that controls transcriptional accessibility through histone modification or chromatin remodeling. These regulators influence differentiation, DNA repair and oncogenic transcriptional programs.
Expected localization
Typically nuclear, often enriched in chromatin-associated complexes.
Research context
This target is frequently studied in the context of Molecular & Cellular Biology research. Application suitability (e.g., IHC, WB) is indicated in the specifications; conditions should be optimized by titration.
Recommended experimental notes
- For Western blotting, optimize lysis conditions and include reducing/non-reducing conditions as appropriate; titrate antibody to balance sensitivity and background.
- For IHC, fixation and antigen retrieval strongly influence epitope accessibility; test citrate- vs EDTA-based retrieval and include matched positive/negative tissues.
Controls & interpretation
Where possible, confirm specificity using genetic perturbation (KO/KD/CRISPR), peptide competition (if applicable), or an orthogonal readout. Include a negative control sample expected to express low/none of DNMT3L, and a positive control sample known to express DNMT3L.
For research use only. Not for diagnostic procedures.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
