| Field | Specification |
|---|---|
| Target | |
| Alternative names | Dopamine receptor D5; D(1B) dopamine receptor; D(5) dopamine receptor; D1beta dopamine receptor; Dopamine D5 receptor; DRD5; DRD1B; DRD1L2 |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | E.coli-derived human DRD5 recombinant protein (Position: M1-H477). Human DRD5 shares 82.3% and 82.4% amino acid (aa) sequence identity with mouse and rat DRD5, respectively. |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody detects dopamine receptor D5 (gene DRD5) in human, mouse and rat samples and is validated for Western blot, flow cytometry and ELISA.
Dopamine receptor D5 (DRD5) is a D1-class G protein-coupled receptor that stimulates adenylyl cyclase through Gs. It binds dopamine with higher affinity than DRD1 but is expressed at lower levels, mainly in the hippocampus and other limbic regions, and is studied in learning, memory and dopamine signaling.
| Target | Dopamine receptor D5 (gene DRD5; UniProt P21918, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / IgG |
| Reactivity | Human, Mouse, Rat |
| Purification | Immunogen affinity purified |
| Form | Lyophilized |
| Formulation | Per vial: 4 mg trehalose; 0.9 mg NaCl; 0.2 mg Na2HPO4 |
| Reconstitution | 500 µg/mL after adding 0.2 mL distilled water |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.25–0.5 µg/mL (Human, Mouse, Rat) |
|---|---|
| Flow cytometry (fixed cells) | 1–3 µg/1×106 cells (Human) |
| ELISA | 0.1–0.5 µg/mL |
Immunogen
Recombinant human DRD5 fragment (Met1–His477), expressed in E. coli. Sequence identity with the mouse and rat orthologs: 82.3% and 82.4%, respectively.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places dopamine receptor D5 in the cell membrane. Tissue expression noted by UniProt (human): Neuron-specific, localized primarily within limbic regions of the brain.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
