| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Elastin;Tropoelastin;ELN; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Gene ID | |
| Host | |
| Immunogen | Bovine alpha-elastin. |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Overview
Anti-Elastin ELN Antibody (Monoclonal, BA-4) is an antibody targeting ELN. Common applications include IHC. Key specifications include host: Mouse; clonality: Monoclonal; clone: Clone: BA-4; isotype: Mouse IgG1; reactivity: Bovine,Human; observed MW: 426 kDa; calculated MW: 68469 MW.
Boster Bio Anti-Elastin ELN Antibody (Monoclonal, BA-4) catalog # MA1038. Tested in IHC applications. This antibody reacts with Bovine, Human.
Key elements and design rationale
- Target: ELN — Elastin
- Antibody format: Host: Mouse; Clonality: Monoclonal; Clone: Clone: BA-4; Isotype: Mouse IgG1
- Species reactivity: Bovine,Human
- Molecular weight guidance: Observed: 426 kDa; Calculated: 68469 MW
Specificity note: No cross reactivity with other proteins.
Biological background
Protein function (datasheet): Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle (By similarity). .
Scientific background (datasheet): Elastin is a major structural protein of tissues such as aorta, which must expand rapidly and recover completely. Elastin chains are cross-linked together into an extensible 3D network. It is a molecular determinant of late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle. Defects in elastin are a cause of autosomal dominant cutis laxa.
Cellular localization (datasheet): Secreted, extracellular space, extracellular matrix . Extracellular matrix of elastic fibers. .
Tissue details (datasheet): Expressed within the outer myometrial smooth muscle and throughout the arteriolar tree of uterus (at protein level). Also expressed in the large arteries, lung and skin. .
Sequence similarities (datasheet): Belongs to the elastin family.
Research relevance and current trends
- Commonly studied in contexts related to Cardiovascular,Cytoskeleton/ECM,ECM Proteins,Extracellular Matrix,Signal Transduction,Vasculature.
- Supports comparative expression analysis across conditions, genotypes, or treatments when paired with appropriate controls.
- Useful for confirming target presence and subcellular distribution using orthogonal readouts (e.g., microscopy vs. immunoblotting).
Common research applications
- Immunohistochemistry (IHC): Assess tissue distribution and cell-type patterns; interpret staining with appropriate negative controls and antigen context.
Notes for experimental interpretation
- Consider isoforms, post-translational modifications, and processing that can shift apparent molecular weight or localization.
- Cross-reactivity (datasheet): No cross-reactivity with other proteins
- Use appropriate positive and negative controls (e.g., KO/KD, blocking peptide, or isotype controls) to support specificity interpretation.
As a monoclonal antibody, this reagent is expected to recognize a defined epitope, which can support consistency across lots when epitope accessibility is preserved.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
