| Field | Specification |
|---|---|
| Target | |
| Alternative names | C-C motif chemokine 26;CC chemokine IMAC;Eotaxin-3;Macrophage inflammatory protein 4-alpha;MIP-4-alpha;Small-inducible cytokine A26;Thymic stroma chemokine-1;TSC-1;CCL26;SCYA26;UNQ216/PRO242; |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human Eotaxin 3. |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody detects C-C motif chemokine 26 (gene CCL26) in human samples and is validated for Western blot. The predicted molecular weight is 10.6 kDa, and the supplier reports an observed band at about 11 kDa.
CCL26 (also called eotaxin-3) is a C-C chemokine that attracts eosinophils and basophils, mainly by binding CCR3, and it can also act on CX3CR1. It is strongly induced by the Th2 cytokines IL-4 and IL-13 and is one of the most upregulated genes in eosinophilic esophagitis, making it a common marker in allergic inflammation research.
| Target | C-C motif chemokine 26 (gene CCL26; UniProt Q9Y258, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / Rabbit IgG |
| Reactivity | Human |
| Form | Lyophilized |
| Formulation | Per vial: 0.9 mg NaCl; 0.2 mg Na2HPO4; 0.05 mg thimerosal; 0.05 mg NaN3; plus stabilizers |
| Calculated MW | 10.6 kDa |
| Observed MW | 11 kDa |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.1–0.5 µg/mL (Human) |
|---|
Samples with a confirmed band (WB): COLO320 cells, A549 cells.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide from the C-terminal region of human eotaxin 3.
Reactivity Notes
The supplier lists reactivity with human. UniProt describes C-C motif chemokine 26 as a secreted protein. Tissue expression noted by UniProt (human): Ubiquitously expressed at low levels in various tissues including heart and ovary. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
